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The Hippo pathway origin and its oncogenic alteration in evolution

The Hippo pathway origin and its oncogenic alteration in evolution

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2313439861

The Hippo pathway origin and its oncogenic alteration in evolution

About this item

Full title

The Hippo pathway origin and its oncogenic alteration in evolution

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in Drosophila, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals; however, how this pathway was evolved to be functional from its origin is still largely unknown....

Alternative Titles

Full title

The Hippo pathway origin and its oncogenic alteration in evolution

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2313439861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2313439861

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/837500