The Hippo pathway origin and its oncogenic alteration in evolution
The Hippo pathway origin and its oncogenic alteration in evolution
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in Drosophila, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals; however, how this pathway was evolved to be functional from its origin is still largely unknown....
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The Hippo pathway origin and its oncogenic alteration in evolution
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TN_cdi_proquest_journals_2313439861
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2313439861
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E-ISSN
2692-8205
DOI
10.1101/837500
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https://www.proquest.com/docview/2313439861?pq-origsite=primo&accountid=13902