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Transferrin receptor 1: a target for antibody-mediated cancer therapy

Transferrin receptor 1: a target for antibody-mediated cancer therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2323411212

Transferrin receptor 1: a target for antibody-mediated cancer therapy

About this item

Full title

Transferrin receptor 1: a target for antibody-mediated cancer therapy

Publisher

London: Future Medicine Ltd

Journal title

Immunotherapy, 2016-09, Vol.8 (9), p.991-994

Language

English

Formats

Publication information

Publisher

London: Future Medicine Ltd

More information

Scope and Contents

Contents

Iron is a cofactor of intracellular enzymes including the ribonucleotide reductase that is coupled to DNA synthesis and, thus, required for cellular proliferation. [...]although TfR1 is expressed at a low level in a broad variety of cells, it is expressed at higher levels in rapidly proliferating cells, including malignant cells in which overexpres...

Alternative Titles

Full title

Transferrin receptor 1: a target for antibody-mediated cancer therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2323411212

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2323411212

Other Identifiers

ISSN

1750-743X

E-ISSN

1750-7448

DOI

10.2217/imt-2016-0050

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