Transferrin receptor 1: a target for antibody-mediated cancer therapy
Transferrin receptor 1: a target for antibody-mediated cancer therapy
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Publisher
London: Future Medicine Ltd
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Language
English
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Publisher
London: Future Medicine Ltd
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Contents
Iron is a cofactor of intracellular enzymes including the ribonucleotide reductase that is coupled to DNA synthesis and, thus, required for cellular proliferation. [...]although TfR1 is expressed at a low level in a broad variety of cells, it is expressed at higher levels in rapidly proliferating cells, including malignant cells in which overexpres...
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Full title
Transferrin receptor 1: a target for antibody-mediated cancer therapy
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TN_cdi_proquest_journals_2323411212
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2323411212
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ISSN
1750-743X
E-ISSN
1750-7448
DOI
10.2217/imt-2016-0050