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Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2343249911

Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

About this item

Full title

Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

Publisher

New York: Springer US

Journal title

Metabolic brain disease, 2020-01, Vol.35 (1), p.11-30

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Extracellular senile plaques and intracellular neurofibrillary tangles are the neuropathological findings of the Alzheimer’s disease (AD). Based on the amyloid cascade hypothesis, the main component of senile plaques, the amyloid-beta (Aβ) peptide, and its derivative called amyloid precursor protein (APP) both have been found to place their central...

Alternative Titles

Full title

Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2343249911

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2343249911

Other Identifiers

ISSN

0885-7490

E-ISSN

1573-7365

DOI

10.1007/s11011-019-00516-y

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