Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia
Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Increasing evidence suggests a role for interferons (IFNs) in neurodegeneration. Parkinson's disease (PD) associated kinase LRRK2 has been implicated in IFN type II (IFN) response in infections and nigral neuronal loss. However, whether and how LRRK2 synergizes with IFN-γ still remains unclear. Here, we employed dopaminergic (DA) neurons and microg...
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Full title
Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia
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TN_cdi_proquest_journals_2349085878
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2349085878
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E-ISSN
2692-8205
DOI
10.1101/2020.01.30.925222
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https://www.proquest.com/docview/2349085878?pq-origsite=primo&accountid=13902
