143 The Combination of anti-TIM-3 and anti-PD-1 Checkpoint Inhibitors With Focused Radiation Resulte...
143 The Combination of anti-TIM-3 and anti-PD-1 Checkpoint Inhibitors With Focused Radiation Resulted in a Synergistic Antitumor Immune Response in a Preclinical Glioma Model
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Philadelphia: Oxford University Press
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English
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Philadelphia: Oxford University Press
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INTRODUCTION:
Checkpoint molecules like programmed death-1 (PD-1) and T-cell immunoglobulin mucin-3 (TIM-3) act as negative regulators of the immune system and can be upregulated in the setting of glioblastoma multiforme (GBM). Combined PD-1 blockade and stereotactic radiosurgery (SRS) have been shown to improve antitumor immunity an...
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143 The Combination of anti-TIM-3 and anti-PD-1 Checkpoint Inhibitors With Focused Radiation Resulted in a Synergistic Antitumor Immune Response in a Preclinical Glioma Model
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TN_cdi_proquest_journals_2357586530
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2357586530
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0148-396X
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1524-4040
DOI
10.1227/01.neu.0000467105.60300.04
