Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition...
Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition during pancreatic carcinogenesis
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England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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English
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England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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ObjectiveSETD2, the sole histone H3K36 trimethyltransferase, is frequently mutated or deleted in human cancer, including pancreatic ductal adenocarcinoma (PDAC). However, whether SETD2/H3K36me3 alteration results in PDAC remains largely unknown.DesignTCGA(PAAD) public database and PDAC tissue array with SETD2/H3K36me3 staining were used to investig...
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Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition during pancreatic carcinogenesis
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TN_cdi_proquest_journals_2372614724
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2372614724
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ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2019-318362
