Molecular architecture of thyroglobulin revealed
Molecular architecture of thyroglobulin revealed
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London: Nature Publishing Group
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English
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London: Nature Publishing Group
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On page 627, Coscia et al.2 report the first structure of full-length human thyroglobulin and identify its hormone-forming tyrosine amino-acid residues, thereby filling a crucial gap in our knowledge of the biosynthetic pathway of the thyroid hormones. Using the cryo-EM data, the authors built an atomic model of the protein that contained 93% of it...
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Molecular architecture of thyroglobulin revealed
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TN_cdi_proquest_journals_2374217799
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2374217799
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/d41586-020-00244-9