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The Zinc Finger Antiviral Protein restricts SARS-CoV-2

The Zinc Finger Antiviral Protein restricts SARS-CoV-2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2410538902

The Zinc Finger Antiviral Protein restricts SARS-CoV-2

About this item

Full title

The Zinc Finger Antiviral Protein restricts SARS-CoV-2

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Recent evidence shows that the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is highly sensitive to interferons (IFNs). However, the underlying antiviral effectors remain to be defined. Here, we show that Zinc finger antiviral protein (ZAP) that specifically targets CpG dinucleotides in viral RNA sequences restricts SARS-CoV-2. We de...

Alternative Titles

Full title

The Zinc Finger Antiviral Protein restricts SARS-CoV-2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2410538902

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2410538902

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.06.04.134379