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Microbiota-derived short chain fatty acids promote Aβ plaque deposition

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Microbiota-derived short chain fatty acids promote Aβ plaque deposition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2411344596

Microbiota-derived short chain fatty acids promote Aβ plaque deposition

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Cold Spring Harbor: Cold Spring Harbor Laboratory Press

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Contents

Previous studies have identified a crucial role of the gut microbiome in modifying Alzheimer's disease (AD) progression. However, the mechanisms of microbiome-brain interaction in AD, including the microbial mediators and their cellular targets in the brain, were so far unknown. Here, we identify microbiota-derived short chain fatty acids (SCFA) as...

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Full title

Microbiota-derived short chain fatty acids promote Aβ plaque deposition

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Record Identifier

TN_cdi_proquest_journals_2411344596

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2411344596

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E-ISSN

2692-8205

DOI

10.1101/2020.06.09.141879

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https://www.proquest.com/docview/2411344596?pq-origsite=primo&accountid=13902

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