Endogenous Rab29 does not impact basal or nigericin and monensin stimulated LRRK2 pathway activity
Endogenous Rab29 does not impact basal or nigericin and monensin stimulated LRRK2 pathway activity
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Mutations that enhance LRRK2 protein kinase activity cause inherited Parkinson’s disease. LRRK2 phosphorylates a group of Rab GTPase proteins, including Rab10 and Rab12, within the effector-binding switch-II motif. Previous work has indicated that the PARK16 locus, which harbors the gene encoding for Rab29, is involved in Parkinson’s, and...
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Endogenous Rab29 does not impact basal or nigericin and monensin stimulated LRRK2 pathway activity
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TN_cdi_proquest_journals_2411628941
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2411628941
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2692-8205
DOI
10.1101/2020.06.08.139675
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https://www.proquest.com/docview/2411628941?pq-origsite=primo&accountid=13902
