New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine
New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
Several clinical guidelines recommend genetic screening of
DPYD
, including coverage of the variants c.1905 + 1G>A(
DPYD
*2A), c.1679T>G(
DPYD
*13), c.2846A>T, and c.1129-5923C>G, before initiating treatment with fluoropyrimidines. However, this screening is often inadequate at predicting the occurrence of severe fluoro...
Alternative Titles
Full title
New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2420336221
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2420336221
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-020-04093-1
