A TRADE-OFF BETWEEN RESISTANCE TO INFECTION AND REPRODUCTION IN PRIMATE EVOLUTION
A TRADE-OFF BETWEEN RESISTANCE TO INFECTION AND REPRODUCTION IN PRIMATE EVOLUTION
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Most mammals express a functional GGTA1 gene encoding the N-acetyllactosaminide α-1,3-galactosyltransferase enzyme, which synthesizes Galα1-3Galβ1-4GlcNAc (αGal) and are thus tolerant to this self-expressed glycan epitope. Old World primates including humans, however, carry GGTA1 loss-of-function mutations and lack αGal. Presumably, fixation of suc...
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Full title
A TRADE-OFF BETWEEN RESISTANCE TO INFECTION AND REPRODUCTION IN PRIMATE EVOLUTION
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TN_cdi_proquest_journals_2422919448
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2422919448
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E-ISSN
2692-8205
DOI
10.1101/2020.07.10.186742
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https://www.proquest.com/docview/2422919448?pq-origsite=primo&accountid=13902
