Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein...
Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein levels
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Publisher
Tokyo: Springer Japan
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Language
English
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Publisher
Tokyo: Springer Japan
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Contents
The ATP-binding cassette transporter A1 encoded by
ABCA1
plays an integral role in the efflux of cellular cholesterol and phospholipids, but may also be a central mediator of β-amyloid (Aβ) processing. Here, genetic association of the common R219K variant of
ABCA1
is shown with cerebrospinal fluid (CSF) Aβ
1–42
levels, reinforcing...
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Full title
Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein levels
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TN_cdi_proquest_journals_2425620096
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425620096
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ISSN
1434-5161
E-ISSN
1435-232X
DOI
10.1007/s10038-005-0341-x