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Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein...

Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425620096

Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein levels

About this item

Full title

Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein levels

Publisher

Tokyo: Springer Japan

Journal title

Journal of human genetics, 2006-03, Vol.51 (3), p.171-179

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

The ATP-binding cassette transporter A1 encoded by
ABCA1
plays an integral role in the efflux of cellular cholesterol and phospholipids, but may also be a central mediator of β-amyloid (Aβ) processing. Here, genetic association of the common R219K variant of
ABCA1
is shown with cerebrospinal fluid (CSF) Aβ
1–42
levels, reinforcing...

Alternative Titles

Full title

Quantitative trait loci in ABCA1 modify cerebrospinal fluid amyloid-β1-42 and plasma apolipoprotein levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2425620096

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425620096

Other Identifiers

ISSN

1434-5161

E-ISSN

1435-232X

DOI

10.1007/s10038-005-0341-x

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