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Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL14...

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL14...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425648564

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1–2 trial

About this item

Full title

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1–2 trial

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2020-04, Vol.21 (4), p.541-550

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

SummaryBackgroundImmune checkpoint inhibitors targeting PD-1 have shown clinical benefit in adults with cancer, but data on these drugs in children are scarce. We did a phase 1–2 study of nivolumab, a PD-1 blocking monoclonal antibody, to determine its safety, pharmacokinetics, and antitumour activity in children and young adults with recurrent or...

Alternative Titles

Full title

Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1–2 trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2425648564

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425648564

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(20)30023-1

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