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Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturb...

Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturb...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425657303

Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturbed during chronic alcohol consumption

About this item

Full title

Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturbed during chronic alcohol consumption

Publisher

United States: Elsevier Inc

Journal title

Alcohol (Fayetteville, N.Y.), 2020-03, Vol.83, p.17-28

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

AbstractChronic ethanol consumption in high doses is associated with constitutively elevated activity of the serum alcohol dehydrogenase I (ADH I) isoform, which demonstrates a high affinity not only for ethanol but also for a number of bioamine metabolites. Such excessive ADH activity is probably associated with disruptions in the metabolism of ne...

Alternative Titles

Full title

Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturbed during chronic alcohol consumption

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2425657303

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425657303

Other Identifiers

ISSN

0741-8329

E-ISSN

1873-6823

DOI

10.1016/j.alcohol.2019.06.006

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