Up to 100-fold speed-up and multiplexing in optimized DNA-PAINT
Up to 100-fold speed-up and multiplexing in optimized DNA-PAINT
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
DNA-PAINT’s imaging speed has recently been significantly enhanced by optimized sequence design and buffer conditions. However, this implementation has not reached an ultimate speed limit and is only applicable to imaging of single targets. To further improve acquisition speed, we introduce concatenated, periodic DNA sequence motifs, yielding up to...
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Full title
Up to 100-fold speed-up and multiplexing in optimized DNA-PAINT
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TN_cdi_proquest_journals_2429349058
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2429349058
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-020-0869-x
