Advances in Exosomes in the Pathogenesis and Diagnosis of Lung Cancer
Advances in Exosomes in the Pathogenesis and Diagnosis of Lung Cancer
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Chinese
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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世界范围内肺癌的发病率居高不下，不论男性还是女性，肺癌均是恶性肿瘤死亡的首位原因。肺癌的早期诊断将显著改善患者的预后，寻找辅助早期肺癌诊断的标志物是当前研究热点。外泌体是由各种细胞分泌的纳米级微囊泡，包含核酸、蛋白质和脂质等多种成分，是细胞间或细胞与组织间信号传递或物质运输的重要载体。独特的富集机制使其具有作为生物标志物的稳定性和特异性。外泌体除参与肺癌肿瘤微环境的形成及新生血管的生成外，还参与化疗、靶向治疗反应及预后评估。诸多研究进展成果为延长肺癌患者生存期带来新的希望。本文就外泌体特异性蛋白和微小RNA（microRNA, miRNA）在肺癌发病、诊断及预后评估中的价值进行综述。 The incidence of lung cancer is high worldwide, and lu...
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Advances in Exosomes in the Pathogenesis and Diagnosis of Lung Cancer
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TN_cdi_proquest_journals_2430976191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2430976191
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ISSN
1009-3419
E-ISSN
1999-6187
DOI
10.3779/j.issn.1009-3419.2020.104.18
