Alpha-ketoglutarate inhibits Regulatory T cell differentiation by coupling lipidome remodelling to m...
Alpha-ketoglutarate inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
About this item
Full title
Author / Creator
Matias, Maria , Yong, Carmen S , oushani, Amir , Sezgin, Erdinc , Levental, Kandice R , Talebi, Ali , Mongellaz, Cedric , Dehair, Jonas , Wong, Madeline , Chavakis, Triantafyllos , Kinet, Sandrina , Zimmermann, Valerie S , Levental, Ilya , Yvan-Charvet, Laurent , Swinnen, Johannes V , Muljo, Stefan , Tardito, Saverio , Dardalhon, Valerie and Taylor, Naomi
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
The differentiation of CD4 T cells to a specific effector fate is metabolically regulated, integrating glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) with transcriptional and epigenetic changes. OXPHOS is tightly coordinated with the tricarboxylic acid (TCA) cycle but the precise role of TCA intermediates in CD4 T cell differentiat...
Alternative Titles
Full title
Alpha-ketoglutarate inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
Authors, Artists and Contributors
Author / Creator
Yong, Carmen S
oushani, Amir
Sezgin, Erdinc
Levental, Kandice R
Talebi, Ali
Mongellaz, Cedric
Dehair, Jonas
Wong, Madeline
Chavakis, Triantafyllos
Kinet, Sandrina
Zimmermann, Valerie S
Levental, Ilya
Yvan-Charvet, Laurent
Swinnen, Johannes V
Muljo, Stefan
Tardito, Saverio
Dardalhon, Valerie
Taylor, Naomi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2436702152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2436702152
Other Identifiers
DOI
10.1101/2020.08.24.256560
How to access this item
https://www.proquest.com/docview/2436702152?pq-origsite=primo&accountid=13902
