FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age
About this item
Full title
Author / Creator
García-Prat, Laura , Perdiguero, Eusebio , Alonso-Martín, Sonia , Dell’Orso, Stefania , Ravichandran, Srikanth , Brooks, Stephen R. , Juan, Aster H. , Campanario, Silvia , Jiang, Kan , Hong, Xiaotong , Ortet, Laura , Ruiz-Bonilla, Vanessa , Flández, Marta , Moiseeva, Victoria , Rebollo, Elena , Jardí, Mercè , Sun, Hong-Wei , Musarò, Antonio , Sandri, Marco , del Sol, Antonio , Sartorelli, Vittorio and Muñoz-Cánoves, Pura
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tissue regeneration declines with ageing but little is known about whether this arises from changes in stem-cell heterogeneity. Here, in homeostatic skeletal muscle, we identify two quiescent stem-cell states distinguished by relative CD34 expression: CD34
High
, with stemness properties (genuine state), and CD34
Low
, committed to myog...
Alternative Titles
Full title
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age
Authors, Artists and Contributors
Author / Creator
Perdiguero, Eusebio
Alonso-Martín, Sonia
Dell’Orso, Stefania
Ravichandran, Srikanth
Brooks, Stephen R.
Juan, Aster H.
Campanario, Silvia
Jiang, Kan
Hong, Xiaotong
Ortet, Laura
Ruiz-Bonilla, Vanessa
Flández, Marta
Moiseeva, Victoria
Rebollo, Elena
Jardí, Mercè
Sun, Hong-Wei
Musarò, Antonio
Sandri, Marco
del Sol, Antonio
Sartorelli, Vittorio
Muñoz-Cánoves, Pura
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2471529817
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2471529817
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-00593-7
