Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the im...
Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy
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Author / Creator
Nieto, Juan C. , Roldán, Elisa , Jiménez, Isabel , Fox, Laura , Carabia, Júlia , Ortí, Guillermo , Puigdefàbregas, Lluís , Gallur, Laura , Iacoboni, Gloria , Raheja, Priyanka , Pérez, Ana , Bobillo, Sabela , Salamero, Olga , Palacio, Carlos , Valcárcel, David , Crespo, Marta , Bosch, Francesc and Barba, Pere
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Patients receiving an allogeneic hematopoietic cell transplantation (allo-HCT) after the use of PD-1 inhibitors seem to be at a higher risk of developing acute graft-versus-host disease (aGHVD) through etiopathogenetic mechanisms not fully elucidated. Herein, we investigated the effect of nivolumab administered prior to allo-HCT on the following ea...
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Full title
Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy
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TN_cdi_proquest_journals_2473246088
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2473246088
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-0851-8