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Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the im...

Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the im...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2473246088

Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy

About this item

Full title

Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2020-12, Vol.34 (12), p.3420-3425

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Patients receiving an allogeneic hematopoietic cell transplantation (allo-HCT) after the use of PD-1 inhibitors seem to be at a higher risk of developing acute graft-versus-host disease (aGHVD) through etiopathogenetic mechanisms not fully elucidated. Herein, we investigated the effect of nivolumab administered prior to allo-HCT on the following ea...

Alternative Titles

Full title

Posttransplant cyclophosphamide after allogeneic hematopoietic cell transplantation mitigates the immune activation induced by previous nivolumab therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2473246088

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2473246088

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/s41375-020-0851-8

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