Exploiting the folate receptor α in oncology
Exploiting the folate receptor α in oncology
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Folate receptor α (FRα) came into focus as an anticancer target many decades after the successful development of drugs targeting intracellular folate metabolism, such as methotrexate and pemetrexed. Binding to FRα is one of several methods by which folate is taken up by cells; however, this receptor is an attractive anticancer drug target owing to...
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Full title
Exploiting the folate receptor α in oncology
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TN_cdi_proquest_journals_2476740349
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476740349
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/s41571-020-0339-5
