Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients
Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients
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England: Nature Publishing Group
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English
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England: Nature Publishing Group
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Sertraline is an (SSRI-)antidepressant metabolized by the polymorphic CYP2C19 enzyme. The aim of this study was to investigate the impact of CYP2C19 genotype on the serum concentrations of sertraline in a large patient population. Second, the proportions of patients in the various CYP2C19 genotype-defined subgroups obtaining serum concentrations ou...
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Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients
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TN_cdi_proquest_journals_2476741868
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476741868
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-019-0554-x