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Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476741868

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

About this item

Full title

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

Publisher

England: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2020-02, Vol.45 (3), p.570-576

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Sertraline is an (SSRI-)antidepressant metabolized by the polymorphic CYP2C19 enzyme. The aim of this study was to investigate the impact of CYP2C19 genotype on the serum concentrations of sertraline in a large patient population. Second, the proportions of patients in the various CYP2C19 genotype-defined subgroups obtaining serum concentrations ou...

Alternative Titles

Full title

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2476741868

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476741868

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/s41386-019-0554-x

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