Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer:...
Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial
About this item
Full title
Author / Creator
Lheureux, Stephanie , Cristea, Mihaela C , Bruce, Jeffrey P , Garg, Swati , Cabanero, Michael , Mantia-Smaldone, Gina , Olawaiye, Alexander B , Ellard, Susan L , Weberpals, Johanne I , Wahner Hendrickson, Andrea E , Fleming, Gini F , Welch, Stephen , Dhani, Neesha C , Stockley, Tracy , Rath, Prisni , Karakasis, Katherine , Jones, Gemma N , Jenkins, Suzanne , Rodriguez-Canales, Jaime , Tracy, Michael , Tan, Qian , Bowering, Valerie , Udagani, Smitha , Wang, Lisa , Kunos, Charles A , Chen, Eric , Pugh, Trevor J and Oza, Amit M
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
The Wee1 (WEE1hu) inhibitor adavosertib and gemcitabine have shown preclinical synergy and promising activity in early phase clinical trials. We aimed to determine the efficacy of this combination in patients with ovarian cancer.
In this double-blind, randomised, placebo-controlled, phase 2 trial, women with measurable recurrent platinum-resista...
Alternative Titles
Full title
Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Cristea, Mihaela C
Bruce, Jeffrey P
Garg, Swati
Cabanero, Michael
Mantia-Smaldone, Gina
Olawaiye, Alexander B
Ellard, Susan L
Weberpals, Johanne I
Wahner Hendrickson, Andrea E
Fleming, Gini F
Welch, Stephen
Dhani, Neesha C
Stockley, Tracy
Rath, Prisni
Karakasis, Katherine
Jones, Gemma N
Jenkins, Suzanne
Rodriguez-Canales, Jaime
Tracy, Michael
Tan, Qian
Bowering, Valerie
Udagani, Smitha
Wang, Lisa
Kunos, Charles A
Chen, Eric
Pugh, Trevor J
Oza, Amit M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2479690224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2479690224
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(20)32554-X
