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Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult...

Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2484413627

Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult T-cell leukemia cells

About this item

Full title

Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult T-cell leukemia cells

Publisher

New York: Springer US

Journal title

Investigational new drugs, 2021-02, Vol.39 (1), p.122-130

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Summary
Adult T cell leukemia (ATL) is an aggressive and malignant blood disease. We previously reported that steroid-structured cucurbitacin D (CuD) induces apoptosis in ATL cells. In this study, we investigated the effects of mitogen-activated protein kinase (MAPK) signaling inhibitors on CuD-induced cell death in peripheral blood lymphocytes...

Alternative Titles

Full title

Mitogen-activated protein kinases are involved in cucurbitacin D-induced antitumor effects on adult T-cell leukemia cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2484413627

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2484413627

Other Identifiers

ISSN

0167-6997

E-ISSN

1573-0646

DOI

10.1007/s10637-020-00997-0

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