TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibiti...
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition
About this item
Full title
Author / Creator
Bamezai, Shiva , Demir, Deniz , Pulikkottil, Alex Jose , Ciccarone, Fabio , Fischbein, Elena , Sinha, Amit , Borga, Chiara , te Kronnie, Geertruy , Meyer, Lüder-Hinrich , Mohr, Fabian , Götze, Maria , Caiafa, Paola , Debatin, Klaus-Michael , Döhner, Konstanze , Döhner, Hartmut , González-Menéndez, Irene , Quintanilla-Fend, Leticia , Herold, Tobias , Jeremias, Irmela , Feuring-Buske, Michaela , Buske, Christian and Rawat, Vijay P. S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer characterized by skewed epigenetic patterns, raising the possibility of therapeutically targeting epigenetic factors in this disease. Here we report that among different cancer types, epigenetic factor
TET1
is highly expressed in T-ALL and is crucial for human T...
Alternative Titles
Full title
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition
Authors, Artists and Contributors
Author / Creator
Demir, Deniz
Pulikkottil, Alex Jose
Ciccarone, Fabio
Fischbein, Elena
Sinha, Amit
Borga, Chiara
te Kronnie, Geertruy
Meyer, Lüder-Hinrich
Mohr, Fabian
Götze, Maria
Caiafa, Paola
Debatin, Klaus-Michael
Döhner, Konstanze
Döhner, Hartmut
González-Menéndez, Irene
Quintanilla-Fend, Leticia
Herold, Tobias
Jeremias, Irmela
Feuring-Buske, Michaela
Buske, Christian
Rawat, Vijay P. S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2486293887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2486293887
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-020-0864-3
