Effects of β-HPV on DNA damage response pathways to drive carcinogenesis: a review
Effects of β-HPV on DNA damage response pathways to drive carcinogenesis: a review
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
The DDR is a complex signaling network responsible for the preservation of genomic integrity. Beta human papillomaviruses (β-HPVs) are able to destabilize the host genome by attenuating the DDR machinery at the molecular scale following expression of the oncogenes E6 and E7. In the event of β-HPV infection, the E6- and E7-mediated inhibition of the...
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Full title
Effects of β-HPV on DNA damage response pathways to drive carcinogenesis: a review
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TN_cdi_proquest_journals_2487161520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2487161520
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ISSN
0920-8569
E-ISSN
1572-994X
DOI
10.1007/s11262-020-01813-w
