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Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the inf...

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the inf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505702365

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted heart

About this item

Full title

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted heart

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract In the adult heart, the epicardium becomes activated after injury, contributing to cardiac healing by secretion of paracrine factors. Here we analyzed by single-cell RNA sequencing combined with RNA in situ hybridization and lineage tracing of WT1+ cells the cellular composition, location, and hierarchy of epicardial stromal cells (EpiSC)...

Alternative Titles

Full title

Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted heart

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2505702365

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505702365

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.01.26.428270