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A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506025042

A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

About this item

Full title

A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract To date, it is still unclear how cancer stem cells (CSCs) regulate their stemness properties, and to what extent they share common features with normal stem cells. Telomerase regulation is a key factor in stem cell maintenance. In this study, we investigate how telomerase regulation affects cancer stem cell biology in pancreatic ductal ade...

Alternative Titles

Full title

A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2506025042

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506025042

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.11.02.361931