Betulonic acid derivatives inhibiting coronavirus replication in cell culture via the nsp15 endoribo...
Betulonic acid derivatives inhibiting coronavirus replication in cell culture via the nsp15 endoribonuclease
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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ABSTRACT The lack of medication to suppress coronavirus infections is a main reason for the dramatic course of the COVID-19 pandemic. There is an urgent need to identify suitable coronavirus drug targets and corresponding lead molecules. Here we describe the discovery of a class of coronavirus inhibitors acting on nsp15, a hexameric protein compone...
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Betulonic acid derivatives inhibiting coronavirus replication in cell culture via the nsp15 endoribonuclease
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TN_cdi_proquest_journals_2506199085
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506199085
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E-ISSN
2692-8205
DOI
10.1101/2020.12.10.418996
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https://www.proquest.com/docview/2506199085?pq-origsite=primo&accountid=13902
