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ArticlesPeer ReviewedFull Text
FraC nanopores with adjustable diameter identify the mass of opposite-charge peptides with 44 dalton resolution
Author / Creator:Huang, Gang ; Voet, Arnout ; Maglia, Giovanni
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-02, Vol.10 (1), p.835-10, Article 835
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Computational design of a self-assembling symmetrical β-propeller protein
Author / Creator:Voet, Arnout R. D. ; Noguchi, Hiroki ; Addy, Christine ; Simoncini, David ; Terada, Daiki ; Unzai, Satoru ; Park, Sam-Yong ; Zhang, Kam Y. J. ; Tame, Jeremy R. H.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15102-15107
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Structure and stability of the designer protein WRAP-T and its permutants
Author / Creator:Mylemans, Bram ; Lee, Xiao Yin ; Laier, Ina ; Helsen, Christine ; Voet, Arnout R. D.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-09, Vol.11 (1), p.18867-18867, Article 18867
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A widely applicable and cost-effective method for specific RNA–protein complex isolation
Author / Creator:Balzarini, Sam ; Van Ende, Roosje ; Voet, Arnout ; Geuten, Koen
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-04, Vol.13 (1), p.6898-19, Article 6898
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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes
Author / Creator:Neggers, Jasper Edgar ; Kwanten, Bert ; Dierckx, Tim ; Noguchi, Hiroki ; Voet, Arnout ; Bral, Lotte ; Minner, Kristien ; Massant, Bob ; Kint, Nicolas ; Delforge, Michel ; Vercruysse, Thomas ; Baloglu, Erkan ; Senapedis, William ; Jacquemyn, Maarten ; Daelemans, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-02, Vol.9 (1), p.502-14, Article 502
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ArticlesPeer ReviewedFull Text
Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
Author / Creator:Terada, Daiki ; Voet, Arnout R. D. ; Noguchi, Hiroki ; Kamata, Kenichi ; Ohki, Mio ; Addy, Christine ; Fujii, Yuki ; Yamamoto, Daiki ; Ozeki, Yasuhiro ; Tame, Jeremy R. H. ; Zhang, Kam Y. J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-07, Vol.7 (1), p.5943-13, Article 5943
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Combining in silico and in cerebro approaches for virtual screening and pose prediction in SAMPL4
Author / Creator:Voet, Arnout R. D. ; Kumar, Ashutosh ; Berenger, Francois ; Zhang, Kam Y. J.
Publisher:Cham: Springer International Publishing
Journal title:Journal of computer-aided molecular design, 2014-04, Vol.28 (4), p.363-373
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Pharmacophore modeling: advances, limitations, and current utility in drug discovery
Author / Creator:Voet, Arnout ; Qing, Xiayu ; Lee, Xiao Yin ; De Raeymaecker, Joren ; Tame, Jeremy ; Zhang, Kam ; De Maeyer, Marc
Publisher:Macclesfield: Dove Medical Press Limited
Journal title:Journal of receptor, ligand and channel research, 2014-01, Vol.7, p.81
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Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
Author / Creator:Christ, Frauke ; Voet, Arnout ; Marchand, Arnaud ; Nicolet, Stefan ; Desimmie, Belete A ; Marchand, Damien ; Bardiot, Dorothée ; Van der Veken, Nam Joo ; Van Remoortel, Barbara ; Strelkov, Sergei V ; De Maeyer, Marc ; Chaltin, Patrick ; Debyser, Zeger
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2010-06, Vol.6 (6), p.442-448
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Reconstruction of Ancestral Metabolic Enzymes Reveals Molecular Mechanisms Underlying Evolutionary Innovation through Gene Duplication
Author / Creator:Voordeckers, Karin ; Brown, Chris A. ; Vanneste, Kevin ; van der Zande, Elisa ; Voet, Arnout ; Maere, Steven ; Verstrepen, Kevin J.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2012-12, Vol.10 (12), p.e1001446
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Computational design of symmetrical eight-bladed β-propeller proteins
Author / Creator:Noguchi, Hiroki ; Addy, Christine ; Simoncini, David ; Wouters, Staf ; Mylemans, Bram ; Van Meervelt, Luc ; Schiex, Thomas ; Zhang, Kam Y. J. ; Tame, Jeremy R. H. ; Voet, Arnout R. D.
Publisher:England: International Union of Crystallography
Journal title:IUCrJ, 2019-01, Vol.6 (1), p.46-55
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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
Author / Creator:Van Loy, Benjamin ; Pujol, Eugènia ; Kamata, Kenichi ; Lee, Xiao Yin ; Bakirtzoglou, Nikolai ; Van Berwaer, Ria ; Vandeput, Julie ; Mestdagh, Cato ; Persoons, Leentje ; De Wijngaert, Brent ; Goovaerts, Quinten ; Noppen, Sam ; Jacquemyn, Maarten ; Ahmadzadeh, Kourosh ; Bernaerts, Eline ; Martín-López, Juan ; Escriche, Celia ; Vanmechelen, Bert ; Krasniqi, Besir ; Singh, Abhimanyu K. ; Daelemans, Dirk ; Maes, Piet ; Matthys, Patrick ; Dehaen, Wim ; Rozenski, Jef ; Das, Kalyan ; Voet, Arnout ; Vázquez, Santiago ; Naesens, Lieve ; Stevaert, Annelies
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2025-02, Vol.21 (2), p.e1012571
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ArticlesPeer ReviewedFull Text
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells
Author / Creator:Sneyers, Flore ; Kerkhofs, Martijn ; Speelman-Rooms, Femke ; Welkenhuyzen, Kirsten ; La Rovere, Rita ; Shemy, Ahmed ; Voet, Arnout ; Eelen, Guy ; Dewerchin, Mieke ; Tait, Stephen W. G. ; Ghesquière, Bart ; Bootman, Martin D. ; Bultynck, Geert
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2023-09, Vol.14 (9), p.600-600, Article 600
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Duplication of a promiscuous transcription factor drives the emergence of a new regulatory network
Author / Creator:Pougach, Ksenia ; Voet, Arnout ; Kondrashov, Fyodor A. ; Voordeckers, Karin ; Christiaens, Joaquin F. ; Baying, Bianka ; Benes, Vladimir ; Sakai, Ryo ; Aerts, Jan ; Zhu, Bo ; Van Dijck, Patrick ; Verstrepen, Kevin J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-09, Vol.5 (1), p.4868, Article 4868
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ArticlesPeer ReviewedFull Text
Functional conservation of HIV-1 Gag: implications for rational drug design
Author / Creator:Li, Guangdi ; Verheyen, Jens ; Rhee, Soo-Yon ; Voet, Arnout ; Vandamme, Anne-Mieke ; Theys, Kristof
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2013-10, Vol.10 (1), p.126-126, Article 126
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A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer
Author / Creator:Smeets, Elien ; Huang, Shengyun ; Lee, Xiao Yin ; Van Nieuwenhove, Erika ; Helsen, Christine ; Handle, Florian ; Moris, Lisa ; El Kharraz, Sarah ; Eerlings, Roy ; Devlies, Wout ; Willemsen, Mathijs ; Bücken, Leoni ; Prezzemolo, Teresa ; Humblet‐Baron, Stephanie ; Voet, Arnout ; Rochtus, Anne ; Van Schepdael, Ann ; Zegher, Francis ; Claessens, Frank
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Journal of cachexia, sarcopenia and muscle, 2022-08, Vol.13 (4), p.2242-2253
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Electrostatic Similarities between Protein and Small Molecule Ligands Facilitate the Design of Protein-Protein Interaction Inhibitors
Author / Creator:Voet, Arnout ; Berenger, Francois ; Zhang, Kam Y. J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e75762-e75762
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Virus Evolution Reveals an Exclusive Role for LEDGF/p75 in Chromosomal Tethering of HIV
Author / Creator:Hombrouck, Anneleen ; De Rijck, Jan ; Hendrix, Jelle ; Vandekerckhove, Linos ; Voet, Arnout ; Maeyer, Marc De ; Witvrouw, Myriam ; Engelborghs, Yves ; Christ, Frauke ; Gijsbers, Rik ; Debyser, Zeger
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2007-03, Vol.3 (3), p.e47
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Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev
Author / Creator:Vercruysse, Thomas ; Boons, Eline ; Venken, Tom ; Vanstreels, Els ; Voet, Arnout ; Steyaert, Jan ; De Maeyer, Marc ; Daelemans, Dirk
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-04, Vol.8 (4), p.e60259
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ArticlesPeer ReviewedFull Text
Fragger: a protein fragment picker for structural queries [version 1; peer review: 2 approved]
Author / Creator:Berenger, Francois ; Simoncini, David ; Voet, Arnout ; Shrestha, Rojan ; Zhang, Kam Y.J
Publisher:England: Faculty of 1000 Ltd
Journal title:F1000 research, 2017, Vol.6, p.1722
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FraC nanopores with adjustable diameter identify the mass of opposite-charge peptides with 44 dalton resolution

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Computational design of a self-assembling symmetrical β-propeller protein

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Structure and stability of the designer protein WRAP-T and its permutants

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A widely applicable and cost-effective method for specific RNA–protein complex isolation

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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes

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Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

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Combining in silico and in cerebro approaches for virtual screening and pose prediction in SAMPL4

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Pharmacophore modeling: advances, limitations, and current utility in drug discovery

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Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

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Reconstruction of Ancestral Metabolic Enzymes Reveals Molecular Mechanisms Underlying Evolutionary Innovation through Gene Duplication

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Computational design of symmetrical eight-bladed β-propeller proteins

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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

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Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells

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Duplication of a promiscuous transcription factor drives the emergence of a new regulatory network

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Functional conservation of HIV-1 Gag: implications for rational drug design

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A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer

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Electrostatic Similarities between Protein and Small Molecule Ligands Facilitate the Design of Protein-Protein Interaction Inhibitors

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Virus Evolution Reveals an Exclusive Role for LEDGF/p75 in Chromosomal Tethering of HIV

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Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev

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Fragger: a protein fragment picker for structural queries [version 1; peer review: 2 approved]

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