Poised cell circuits in human skin are activated in disease
Poised cell circuits in human skin are activated in disease
About this item
Full title
Author / Creator
Reynolds, Gary , Vegh, Peter , Fletcher, James , Poyner, Elizabeth Fm , Stephenson, Emily , Goh, Issac , Botting, Rachel A , Huang, Ni , Olabi, Bayanne , Dubois, Anna , Dixon, David , Green, Kile , Maunder, Daniel , Engelbert, Justin , Efremova, Mirjana , Polański, Krzysztof , Jardine, Laura , Jones, Claire , Ness, Thomas , Horsfall, Dave , Mcgrath, Jim , Carey, Christopher , Popescu, Dorin-Mirel , Webb, Simone , Xiao-Nong Wang , Sayer, Ben , Jong-Eun Park , Negri, Victor A , Belokhvostova, Daria , Lynch, Magnus , Mcdonald, David , Filby, Andrew , Hagai, Tzachi , Meyer, Kerstin B , Husain, Akhtar , Coxhead, Jonathan , Vento-Tormo, Roser , Behjati, Sam , Lisgo, Steven , Villani, Alexandra-Chloé , Bacardit, Jaume , Jones, Phil , Edel A O’toole , Ogg, Graham S , Rajan, Neil , Reynolds, Nick J , Teichmann, Sarah A , Watt, Fiona and Haniffa, Muzlifah
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Abstract The human skin confers biophysical and immunological protection through a complex cellular network that is established early in development. We profiled ~500,000 single cells using RNA-sequencing from healthy adult and developing skin, and skin from patients with atopic dermatitis and psoriasis. Our findings reveal a predominance of innate...
Alternative Titles
Full title
Poised cell circuits in human skin are activated in disease
Authors, Artists and Contributors
Author / Creator
Vegh, Peter
Fletcher, James
Poyner, Elizabeth Fm
Stephenson, Emily
Goh, Issac
Botting, Rachel A
Huang, Ni
Olabi, Bayanne
Dubois, Anna
Dixon, David
Green, Kile
Maunder, Daniel
Engelbert, Justin
Efremova, Mirjana
Polański, Krzysztof
Jardine, Laura
Jones, Claire
Ness, Thomas
Horsfall, Dave
Mcgrath, Jim
Carey, Christopher
Popescu, Dorin-Mirel
Webb, Simone
Xiao-Nong Wang
Sayer, Ben
Jong-Eun Park
Negri, Victor A
Belokhvostova, Daria
Lynch, Magnus
Mcdonald, David
Filby, Andrew
Hagai, Tzachi
Meyer, Kerstin B
Husain, Akhtar
Coxhead, Jonathan
Vento-Tormo, Roser
Behjati, Sam
Lisgo, Steven
Villani, Alexandra-Chloé
Bacardit, Jaume
Jones, Phil
Edel A O’toole
Ogg, Graham S
Rajan, Neil
Reynolds, Nick J
Teichmann, Sarah A
Watt, Fiona
Haniffa, Muzlifah
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2507275450
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507275450
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.11.05.369363
How to access this item
https://www.proquest.com/docview/2507275450?pq-origsite=primo&accountid=13902