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ArticlesPeer ReviewedFull Text
Inherited cylindromas: lessons from a rare tumour
Author / Creator:Rajan, Neil, Dr ; Ashworth, Alan, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-09, Vol.16 (9), p.e460-e469
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ArticlesPeer ReviewedFull Text
CYLD in health and disease
Author / Creator:Marín-Rubio, José L. ; Raote, Ishier ; Inns, Joseph ; Dobson-Stone, Carol ; Rajan, Neil
Publisher:England: Cambridge Company of Biologists
Journal title:Disease models & mechanisms, 2023-06, Vol.16 (6)
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ArticlesPeer ReviewedFull Text
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome
Author / Creator:Davies, Helen R. ; Hodgson, Kirsty ; Schwalbe, Edward ; Coxhead, Jonathan ; Sinclair, Naomi ; Zou, Xueqing ; Cockell, Simon ; Husain, Akhtar ; Nik-Zainal, Serena ; Rajan, Neil
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4717-9, Article 4717
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ArticlesPeer ReviewedFull Text
Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study
Author / Creator:Gault, Abigail ; Hogarth, Linda ; Williams, Kristian C ; Greystoke, Alastair ; Rajan, Neil ; Speight, Ally ; Lamb, Christopher A ; Bridgewood, Alison ; Brown-Schofield, Lisa-Jayne ; Rayner, Fiona ; Isaacs, John D ; Nsengimana, Jérémie ; Stewart, Christopher J ; Anderson, Amy E ; Plummer, Ruth ; Pratt, Arthur G
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2024-06, Vol.24 (1), p.733-11, Article 733
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ArticlesPeer ReviewedFull Text
Transcriptomic profiling of human skin biopsies in the clinical trial setting: A protocol for high quality RNA extraction from skin tumours
Author / Creator:Danilenko, Marina ; Stones, Robert ; Rajan, Neil
Publisher:England: Wellcome Trust Limited
Journal title:Wellcome open research, 2018, Vol.3, p.45-45
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ArticlesPeer ReviewedFull Text
Universal testing of cutaneous sebaceous carcinoma: a missed opportunity in Lynch syndrome detection
Author / Creator:Rajan, Neil ; Cook, Sam ; Best, Katie ; Monahan, Kevin
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2024, Vol.25 (1), p.e1-e2
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ArticlesPeer ReviewedFull Text
Inherited skin tumour syndromes
Author / Creator:Brown, Sarah ; Brennan, Paul ; Rajan, Neil
Publisher:London: Elsevier Ltd
Journal title:Clinical medicine (London, England), 2017-12, Vol.17 (6), p.562-567
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ArticlesPeer ReviewedFull Text
Clinical practice guidelines for the diagnosis and surveillance of BAP1 tumour predisposition syndrome
Author / Creator:Lalloo, Fiona ; Kulkarni, Anju ; Chau, Cindy ; Nielsen, Maartje ; Sheaff, Michael ; Steele, Jeremy ; van Doorn, Remco ; Wadt, Karin ; Hamill, Monica ; Torr, Beth ; Tischkowitz, Marc ; Ahmed, Munaza ; Bajalica-Lagercrantz, Svetlana ; Blatnik, Ana ; Brunet, Joan ; Cleaver, Ruth ; Colas, Chrystelle ; Dabir, Tabib ; Evans, D. Gareth ; Feshtali, Shirin ; Ghiorzo, Paola ; Graversen, Lise ; Griewank, Klaus ; Helgadottir, Hildur ; Jewell, Rosalyn ; Kohut, Kelly ; Lorentzen, Henrik ; Massi, Daniela ; Missotten, Guy ; Murray, Alex ; Murray, Jennie ; Nadal, Ernest ; Ong, Kai Ren ; Piulats, Josep M. ; Puig, Susana ; Rajan, Neil ; Ribero, Simone ; Salle, Galateau ; Teulé, Alexandre ; Tham, Emma ; van Paassen, Barbara ; De Putter, Robin ; Verdijk, Robert ; Wagner, Anja ; Woodward, Emma R. ; Hanson, Helen
Publisher:England: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2023-11, Vol.31 (11), p.1261-1269
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ArticlesPeer ReviewedFull Text
Genetic Testing in CYLD Cutaneous Syndrome: An Update
Author / Creator:Nagy, Nikoletta ; Dubois, Anna ; Szell, Marta ; Rajan, Neil
Publisher:Macclesfield: Dove Medical Press Limited
Journal title:Application of clinical genetics, 2021-01, Vol.14, p.427-444
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ArticlesPeer ReviewedFull Text
Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours: study protocol for a...
Author / Creator:Cranston, Amy ; Stocken, Deborah D. ; Stamp, Elaine ; Roblin, David ; Hamlin, Julia ; Langtry, James ; Plummer, Ruth ; Ashworth, Alan ; Burn, John ; Rajan, Neil
Publisher:England: BioMed Central
Journal title:Current controlled trials in cardiovascular medicine, 2017-03, Vol.18 (1), p.111-111, Article 111
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ArticlesPeer ReviewedFull Text
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
Author / Creator:Rajan, N ; Elliott, R ; Clewes, O ; Mackay, A ; Reis-Filho, J S ; Burn, J ; Langtry, J ; Sieber-Blum, M ; Lord, C J ; Ashworth, A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2011-10, Vol.30 (41), p.4243-4260
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ArticlesFull Text
Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha
Author / Creator:Hodgson, Kirsty ; Inns, Joseph ; Reynolds, Gary ; Stephenson, Emily ; Paul, Andrew ; Sinclair, Naomi ; Berretta, Giacomo ; Lawson, Christopher ; Frey, Andrew Michael ; Ivanova, Iglika ; Adam, Eva ; Lord, Christopher J ; Cockell, Simon ; Coxhead, Jonathan ; Nagy, Nikoletta ; Adams, David ; Szell, Marta ; Trost, Matthias ; Haniffa, Muzlifah ; Mackay, Simon ; Perkins, Neil ; Rajan, Neil
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2025-02
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ArticlesFull Text
Epigenetic dysregulation underpins tumorigenesis in a cutaneous tumor syndrome
Author / Creator:Davies, Helen ; Hodgson, Kirsty ; Schwalbe, Edward ; Coxhead, Jonathan ; Sinclair, Naomi ; Zou, Xueqing ; Cockell, Simon ; Husain, Akhtar ; Nik-Zainal, Serena ; Rajan, Neil
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-07
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ArticlesFull Text
Poised cell circuits in human skin are activated in disease
Author / Creator:Reynolds, Gary ; Vegh, Peter ; Fletcher, James ; Poyner, Elizabeth Fm ; Stephenson, Emily ; Goh, Issac ; Botting, Rachel A ; Huang, Ni ; Olabi, Bayanne ; Dubois, Anna ; Dixon, David ; Green, Kile ; Maunder, Daniel ; Engelbert, Justin ; Efremova, Mirjana ; Polański, Krzysztof ; Jardine, Laura ; Jones, Claire ; Ness, Thomas ; Horsfall, Dave ; Mcgrath, Jim ; Carey, Christopher ; Popescu, Dorin-Mirel ; Webb, Simone ; Xiao-Nong Wang ; Sayer, Ben ; Jong-Eun Park ; Negri, Victor A ; Belokhvostova, Daria ; Lynch, Magnus ; Mcdonald, David ; Filby, Andrew ; Hagai, Tzachi ; Meyer, Kerstin B ; Husain, Akhtar ; Coxhead, Jonathan ; Vento-Tormo, Roser ; Behjati, Sam ; Lisgo, Steven ; Villani, Alexandra-Chloé ; Bacardit, Jaume ; Jones, Phil ; Edel A O’toole ; Ogg, Graham S ; Rajan, Neil ; Reynolds, Nick J ; Teichmann, Sarah A ; Watt, Fiona ; Haniffa, Muzlifah
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-11
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ArticlesPeer ReviewedFull Text
Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial
Author / Creator:Ormerod, Anthony D ; Thomas, Kim S ; Craig, Fiona E ; Mitchell, Eleanor ; Greenlaw, Nicola ; Norrie, John ; Mason, James M ; Walton, Shernaz ; Johnston, Graham A ; Williams, Hywel C
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ (Online), 2015-06, Vol.350 (jun12 3), p.h2958-h2958
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ArticlesPeer ReviewedFull Text
UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial
Author / Creator:Craig, Fiona F ; Thomas, Kim S ; Mitchell, Eleanor J ; Williams, Hywel C ; Norrie, John ; Mason, James M ; Ormerod, Anthony D
Publisher:England: BioMed Central Ltd
Journal title:Current controlled trials in cardiovascular medicine, 2012-04, Vol.13 (1), p.51-51, Article 51
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Inherited cylindromas: lessons from a rare tumour

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CYLD in health and disease

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Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome

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Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study

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Transcriptomic profiling of human skin biopsies in the clinical trial setting: A protocol for high quality RNA extraction from skin tumours

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Universal testing of cutaneous sebaceous carcinoma: a missed opportunity in Lynch syndrome detection

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Inherited skin tumour syndromes

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Clinical practice guidelines for the diagnosis and surveillance of BAP1 tumour predisposition syndrome

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Genetic Testing in CYLD Cutaneous Syndrome: An Update

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Tropomyosin Receptor Antagonism in Cylindromatosis (TRAC), an early phase trial of a topical tropomyosin kinase inhibitor as a treatment for inherited CYLD defective skin tumours: study protocol for a...

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Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours

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Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha

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Epigenetic dysregulation underpins tumorigenesis in a cutaneous tumor syndrome

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Poised cell circuits in human skin are activated in disease

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Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial

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UK Dermatology Clinical Trials Network’s STOP GAP trial (a multicentre trial of prednisolone versus ciclosporin for pyoderma gangrenosum): protocol for a randomised controlled trial

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