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BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507750398

BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

About this item

Full title

BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

in utero electroporation, we identified BMPR-2 as a key regulator for the selective dendrite stabilization. Bmpr2 knockout and its rescue experiments show that BMPR-2 inhibits LIMK without ligands and thereby facilitates dendrite destabilization. In contrast, the overexpression of antagonists and agonists indicate that ligand-bound BMPR-2 stabilize...

Alternative Titles

Full title

BMPR-2 gates activity-dependent stabilization of dendrites during mitral cell remodeling

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2507750398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507750398

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.10.30.358861