Gamete simulation improves polygenic transmission disequilibrium analysis
Gamete simulation improves polygenic transmission disequilibrium analysis
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Polygenic risk scores (PRS) derived from summary statistics of genome-wide association studies (GWAS) have enjoyed great popularity in human genetics research. Applied to population cohorts, PRS can effectively stratify individuals by risk group and has promising applications in early diagnosis and clinical intervention. However, our under...
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Gamete simulation improves polygenic transmission disequilibrium analysis
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TN_cdi_proquest_journals_2507792772
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507792772
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E-ISSN
2692-8205
DOI
10.1101/2020.10.26.355602
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https://www.proquest.com/docview/2507792772?pq-origsite=primo&accountid=13902
