SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in...
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells
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Author / Creator
Coate, Katie C , Cha, Jeeyeon , Shrestha, Shristi , Wang, Wenliang , Gonçalves, Luciana Mateus , Almaça, Joana , Kapp, Meghan E , Fasolino, Maria , Morgan, Ashleigh , Dai, Chunhua , Saunders, Diane C , Bottino, Rita , Aramandla, Radhika , Jenkins, Regina , Stein, Roland , Kaestner, Klaus H , Vahedi, Golnaz , Consortium, Hpap , Brissova, Marcela and Powers, Alvin C
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Reports of new-onset diabetes and diabetic ketoacidosis in individuals with COVID-19 have led to the hypothesis that SARS-CoV-2, the virus that causes COVID-19, is directly cytotoxic to pancreatic islet β cells. This would require binding and entry of SARS-CoV-2 into host β cells via cell surface co-expression of ACE2 and TMPRSS2, the putative rece...
Alternative Titles
Full title
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells
Authors, Artists and Contributors
Author / Creator
Cha, Jeeyeon
Shrestha, Shristi
Wang, Wenliang
Gonçalves, Luciana Mateus
Almaça, Joana
Kapp, Meghan E
Fasolino, Maria
Morgan, Ashleigh
Dai, Chunhua
Saunders, Diane C
Bottino, Rita
Aramandla, Radhika
Jenkins, Regina
Stein, Roland
Kaestner, Klaus H
Vahedi, Golnaz
Consortium, Hpap
Brissova, Marcela
Powers, Alvin C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2507873235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2507873235
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.08.31.275719
