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Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic term...

Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic term...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508014242

Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals

About this item

Full title

Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

ABSTRACT Neuronal extracellular vesicles (EVs) play important roles in intercellular communication and pathogenic protein propagation in neurological disease. However, it remains unclear how cargoes are selectively packaged into neuronal EVs. Here, we show that loss of the endosomal retromer complex leads to accumulation of EV cargoes Amyloid Precu...

Alternative Titles

Full title

Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2508014242

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508014242

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/645713