ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 e...
ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes
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Author / Creator
Ma, Mengjun , Li, Hongyu , Wang, Peng , Yang, Wen , Rujia Mi , Jiang, Yuhang , Lu, Yixuan , Shen, Xin , Sui, Pengfei , Wu, Yanfeng and Shen, Huiyong
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Summary Although angiogenesis-osteogenesis coupling is important in ankylosing spondylitis (AS), therapeutic agents targeting the vasculature remain elusive. Here, we identified activating transcription factor 6 (ATF6) as an important regulator of angiogenesis in AS patients. Firstly, we found that ATF6 and fibroblast growth factor 2 (FGF2) levels...
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Full title
ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes
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TN_cdi_proquest_journals_2508121295
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2508121295
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E-ISSN
2692-8205
DOI
10.1101/2020.10.08.332379
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https://www.proquest.com/docview/2508121295?pq-origsite=primo&accountid=13902
