Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: hom...
Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level
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Author / Creator
Leary, Shay , Gaudieri, Silvana , Parker, Matthew D , Chopra, Abha , James, Ian , Pakala, Suman , Alves, Eric , John, Mina , Lindsey, Benjamin B , Keeley, Alexander J , Rowland-Jones, Sarah L , Swanson, Maurice S , Ostrov, David A , Bubenik, Jodi L , Das, Suman , Sidney, John , Sette, Alessandro , de Silva, Thushan I , Phillips, Elizabeth , Mallal, Simon and COVID-19 Genomics UK (COG-UK) consortium
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Genetic variations across the SARS-CoV-2 genome may influence transmissibility of the virus and the host’s anti-viral immune response, in turn affecting the frequency of variants over-time. In this study, we examined the adjacent amino acid polymorphisms in the nucleocapsid (R203K/G204R) of SARS-CoV-2 that arose on the background of the spike D61...
Alternative Titles
Full title
Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level
Authors, Artists and Contributors
Author / Creator
Gaudieri, Silvana
Parker, Matthew D
Chopra, Abha
James, Ian
Pakala, Suman
Alves, Eric
John, Mina
Lindsey, Benjamin B
Keeley, Alexander J
Rowland-Jones, Sarah L
Swanson, Maurice S
Ostrov, David A
Bubenik, Jodi L
Das, Suman
Sidney, John
Sette, Alessandro
de Silva, Thushan I
Phillips, Elizabeth
Mallal, Simon
COVID-19 Genomics UK (COG-UK) consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2512583974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2512583974
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2020.04.10.029454