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Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fi...

Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2514182887

Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fish

About this item

Full title

Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fish

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The process of sperm-egg fusion is critical for successful fertilization, yet the underpinning mechanisms that regulate these steps have remained unclear in vertebrates. Here, we show that both mouse and zebrafish DCST1 and DCST2 are necessary in sperm to fertilize the egg, similar to their orthologs SPE-42 and SPE-49 in C. elegans and Sneaky in D....

Alternative Titles

Full title

Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fish

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2514182887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2514182887

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.04.18.440256