Somatic mutation landscapes at single-molecule resolution
Somatic mutation landscapes at single-molecule resolution
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Author / Creator
Abascal, Federico , Harvey, Luke M. R. , Mitchell, Emily , Lawson, Andrew R. J. , Lensing, Stefanie V. , Ellis, Peter , Russell, Andrew J. C. , Alcantara, Raul E. , Baez-Ortega, Adrian , Wang, Yichen , Kwa, Eugene Jing , Lee-Six, Henry , Cagan, Alex , Coorens, Tim H. H. , Chapman, Michael Spencer , Olafsson, Sigurgeir , Leonard, Steven , Jones, David , Machado, Heather E. , Davies, Megan , Øbro, Nina F. , Mahubani, Krishnaa T. , Allinson, Kieren , Gerstung, Moritz , Saeb-Parsy, Kourosh , Kent, David G. , Laurenti, Elisa , Stratton, Michael R. , Rahbari, Raheleh , Campbell, Peter J. , Osborne, Robert J. and Martincorena, Iñigo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Somatic mutations drive the development of cancer and may contribute to ageing and other diseases
1
,
2
. Despite their importance, the difficulty of detecting mutations that are only present in single cells or small clones has limited our knowledge of somatic mutagenesis to a minority of tissues. Here, to overcome these limitations, we...
Alternative Titles
Full title
Somatic mutation landscapes at single-molecule resolution
Authors, Artists and Contributors
Author / Creator
Harvey, Luke M. R.
Mitchell, Emily
Lawson, Andrew R. J.
Lensing, Stefanie V.
Ellis, Peter
Russell, Andrew J. C.
Alcantara, Raul E.
Baez-Ortega, Adrian
Wang, Yichen
Kwa, Eugene Jing
Lee-Six, Henry
Cagan, Alex
Coorens, Tim H. H.
Chapman, Michael Spencer
Olafsson, Sigurgeir
Leonard, Steven
Jones, David
Machado, Heather E.
Davies, Megan
Øbro, Nina F.
Mahubani, Krishnaa T.
Allinson, Kieren
Gerstung, Moritz
Saeb-Parsy, Kourosh
Kent, David G.
Laurenti, Elisa
Stratton, Michael R.
Rahbari, Raheleh
Campbell, Peter J.
Osborne, Robert J.
Martincorena, Iñigo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2531704290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2531704290
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03477-4