Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition
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Author / Creator
Blume, Tanja , Deussing, Maximilian , Biechele, Gloria , Peters, Finn , Zott, Benedikt , Schmidt, Claudio , Franzmeier, Nicolai , Wind, Karin , Eckenweber, Florian , Sacher, Christian , Shi, Yuan , Ochs, Katharina , Kleinberger, Gernot , Xiang, Xianyuan , Focke, Carola , Lindner, Simon , Franz-Josef Gildehaus , Beyer, Leonie , Barbara Von Ungern-Sternberg , Bartenstein, Peter , Baumann, Karlheinz , Adelsberger, Helmuth , Rominger, Axel , Cumming, Paul , Willem, Michael , Dorostkar, Mario M , Herms, Jochen and Brendel, Matthias
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Background: We undertook longitudinal β-amyloid positron emission tomography (Aβ-PET) imaging as a translational tool for monitoring of chronic treatment with the peroxisome proliferator-activated receptor gamma (PPARγ) agonist pioglitazone in Aβ model mice. We thus tested the hypothesis this treatment would rescue from increases of the Aβ-PET sign...
Alternative Titles
Full title
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition
Authors, Artists and Contributors
Author / Creator
Deussing, Maximilian
Biechele, Gloria
Peters, Finn
Zott, Benedikt
Schmidt, Claudio
Franzmeier, Nicolai
Wind, Karin
Eckenweber, Florian
Sacher, Christian
Shi, Yuan
Ochs, Katharina
Kleinberger, Gernot
Xiang, Xianyuan
Focke, Carola
Lindner, Simon
Franz-Josef Gildehaus
Beyer, Leonie
Barbara Von Ungern-Sternberg
Bartenstein, Peter
Baumann, Karlheinz
Adelsberger, Helmuth
Rominger, Axel
Cumming, Paul
Willem, Michael
Dorostkar, Mario M
Herms, Jochen
Brendel, Matthias
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Primary Identifiers
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TN_cdi_proquest_journals_2535340753
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2535340753
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E-ISSN
2692-8205
DOI
10.1101/2021.05.30.446348
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https://www.proquest.com/docview/2535340753?pq-origsite=primo&accountid=13902