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Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2547183671

Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

About this item

Full title

Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and changes composition in many species as the organism ages. However, how these changes arise and whether they contribute themselves to aging is poorly understood. We show that in replicatively aging yeast cells attachment of DNA circles to NPCs drives the...

Alternative Titles

Full title

Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2547183671

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2547183671

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.06.28.450139