Specialization of chromatin-bound nuclear pore complexes promotes yeast aging
Specialization of chromatin-bound nuclear pore complexes promotes yeast aging
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and changes composition in many species as the organism ages. However, how these changes arise and whether they contribute themselves to aging is poorly understood. We show that in replicatively aging yeast cells attachment of DNA circles to NPCs drives the...
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Specialization of chromatin-bound nuclear pore complexes promotes yeast aging
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TN_cdi_proquest_journals_2547183671
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2547183671
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E-ISSN
2692-8205
DOI
10.1101/2021.06.28.450139
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https://www.proquest.com/docview/2547183671?pq-origsite=primo&accountid=13902