RETRACTED ARTICLE: Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High M...
RETRACTED ARTICLE: Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1)
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Publisher
New York: BioMed Central
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Language
English
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Publisher
New York: BioMed Central
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Scope and Contents
Contents
High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is released passively during cell injury and necrosis, and secreted actively by immune cells. HMGB1 contains three conserved redox-sensitive cysteine residues: C23 and C45 can form an intramolecular disulfide bond, whereas C106 is unpaired a...
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Full title
RETRACTED ARTICLE: Redox Modification of Cysteine Residues Regulates the Cytokine Activity of High Mobility Group Box-1 (HMGB1)
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TN_cdi_proquest_journals_2547614431
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2547614431
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ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2011.00389