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Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and mo...

Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and mo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2550119999

Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and molecular docking studies

About this item

Full title

Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and molecular docking studies

Publisher

Gebze: ACG Publications

Journal title

Organic communications, 2021-04, Vol.14 (2), p.133-143

Language

English

Formats

Publication information

Publisher

Gebze: ACG Publications

More information

Scope and Contents

Contents

Capsaicin and dihydrocapsaicin were modified at phenolic moieties and allylic of double-bond to provide seven capsaicin and dihydrocapsaicin derivatives. Their structures were assigned by spectroscopic techniques (1D-NMR and MS). All compounds were evaluated as histone deacetylase inhibitors via in vitro fluorometric assay at 100 µM. The results re...

Alternative Titles

Full title

Discovery of new capsaicin and dihydrocapsaicin derivatives as histone deacetylase inhibitors and molecular docking studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2550119999

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2550119999

Other Identifiers

ISSN

1307-6175

E-ISSN

1307-6175

DOI

10.25135/acg.oc.102.21.03.1998

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