Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients w...
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Ionizing radiation causes DNA damage and is a mainstay for cancer treatment, but understanding of its genomic impact is limited. We analyzed mutational spectra following radiotherapy in 190 paired primary and recurrent gliomas from the Glioma Longitudinal Analysis Consortium and 3,693 post-treatment metastatic tumors from the Hartwig Medical Founda...
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Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer
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TN_cdi_proquest_journals_2550309391
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2550309391
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00874-3
