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64 results for Lolkema,+Martijn+P.

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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact
Author / Creator:van Dessel, Lisanne F. ; van Riet, Job ; Smits, Minke ; Zhu, Yanyun ; Hamberg, Paul ; van der Heijden, Michiel S. ; Bergman, Andries M. ; van Oort, Inge M. ; de Wit, Ronald ; Voest, Emile E. ; Steeghs, Neeltje ; Yamaguchi, Takafumi N. ; Livingstone, Julie ; Boutros, Paul C. ; Martens, John W. M. ; Sleijfer, Stefan ; Cuppen, Edwin ; Zwart, Wilbert ; van de Werken, Harmen J. G. ; Mehra, Niven ; Lolkema, Martijn P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-11, Vol.10 (1), p.5251-13, Article 5251
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The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets
Author / Creator:van Riet, Job ; van de Werken, Harmen J. G. ; Cuppen, Edwin ; Eskens, Ferry A. L. M. ; Tesselaar, Margot ; van Veenendaal, Linde M. ; Klümpen, Heinz-Josef ; Dercksen, Marcus W. ; Valk, Gerlof D. ; Lolkema, Martijn P. ; Sleijfer, Stefan ; Mostert, Bianca
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4612-4612, Article 4612
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CopywriteR: DNA copy number detection from off-target sequence data
Author / Creator:Kuilman, Thomas ; Velds, Arno ; Kemper, Kristel ; Ranzani, Marco ; Bombardelli, Lorenzo ; Hoogstraat, Marlous ; Nevedomskaya, Ekaterina ; Xu, Guotai ; de Ruiter, Julian ; Lolkema, Martijn P ; Ylstra, Bauke ; Jonkers, Jos ; Rottenberg, Sven ; Wessels, Lodewyk F ; Adams, David J ; Peeper, Daniel S ; Krijgsman, Oscar
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2015-02, Vol.16, p.49
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Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features
Author / Creator:Mendelaar, Pauline A. J. ; Smid, Marcel ; van Riet, Job ; Angus, Lindsay ; Labots, Mariette ; Steeghs, Neeltje ; Hendriks, Mathijs P. ; Cirkel, Geert A. ; van Rooijen, Johan M. ; Ten Tije, Albert J. ; Lolkema, Martijn P. ; Cuppen, Edwin ; Sleijfer, Stefan ; Martens, John W. M. ; Wilting, Saskia M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.574-574, Article 574
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Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning
Author / Creator:de Jong, Anouk C. ; Danyi, Alexandra ; van Riet, Job ; de Wit, Ronald ; Sjöström, Martin ; Feng, Felix ; de Ridder, Jeroen ; Lolkema, Martijn P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-04, Vol.14 (1), p.1968-1968, Article 1968
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Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples
Author / Creator:Mankor, Joanne M. ; Paats, Marthe S. ; Groenendijk, Floris H. ; Roepman, Paul ; Dinjens, Winand N. M. ; Dubbink, Hendrikus J. ; Sleijfer, Stefan ; Cuppen, Edwin ; Lolkema, Martijn P. J. K.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-03, Vol.122 (7), p.953-956
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Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer
Author / Creator:van Geel, Robin M. J. M. ; van Brummelen, Emilie M. J. ; Eskens, Ferry A. L. M. ; Huijberts, Sanne C. F. A. ; de Vos, Filip Y. F. L. ; Lolkema, Martijn P. J. K. ; Devriese, Lot A. ; Opdam, Frans L. ; Marchetti, Serena ; Steeghs, Neeltje ; Monkhorst, Kim ; Thijssen, Bas ; Rosing, Hilde ; Huitema, Alwin D. R. ; Beijnen, Jos H. ; Bernards, René ; Schellens, Jan H. M.
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-04, Vol.122 (8), p.1166-1174
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A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors
Author / Creator:Gan, Hui K. ; Millward, Michael ; Jalving, Mathilde ; Garrido‐Laguna, Ignacio ; Lickliter, Jason D. ; Schellens, Jan H.M. ; Lolkema, Martijn P. ; Van Herpen, Carla L.M. ; Hug, Bruce ; Tang, Lihua ; O'Connor‐Semmes, Robin ; Gagnon, Robert ; Ellis, Catherine ; Ganji, Gopinath ; Matheny, Christopher ; Drilon, Alexander
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:The oncologist (Dayton, Ohio), 2021-10, Vol.26 (10), p.e1844-e1853
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Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications
Author / Creator:Vis, Daniel J. ; Palit, Sander A. L. ; Corradi, Marie ; Cuppen, Edwin ; Mehra, Niven ; Lolkema, Martijn P. ; Wessels, Lodewyk F. A. ; van der Heijden, Michiel S. ; Zwart, Wilbert ; Bergman, Andries M.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2025-03, Vol.17 (1), p.24-13, Article 24
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mFast‐SeqS ‐based aneuploidy score in circulating cell‐free DNA is a prognostic biomarker in prostate cancer
Author / Creator:Isebia, Khrystany T. ; Mostert, Bianca ; Deger, Teoman ; Kraan, Jaco ; de Weerd, Vanja ; Oomen‐de Hoop, Esther ; Hamberg, Paul ; Haberkorn, Brigitte C. M. ; Helgason, Helgi H. ; de Wit, Ronald ; Mathijssen, Ron H. J. ; Lolkema, Martijn P. ; Wilting, Saskia M. ; van Riet, Job ; Martens, John W. M.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2023-09, Vol.17 (9), p.1898-1907
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High‐throughput isolation of circulating tumor DNA: a comparison of automated platforms
Author / Creator:Dessel, Lisanne F. ; Vitale, Silvia R. ; Helmijr, Jean C. A. ; Wilting, Saskia M. ; Vlugt‐Daane, Michelle ; Oomen‐de Hoop, Esther ; Sleijfer, Stefan ; Martens, John W. M. ; Jansen, Maurice P. H. M. ; Lolkema, Martijn P.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2019-02, Vol.13 (2), p.392-402
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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phas...
Author / Creator:Lau, Sai Ping ; van ’t Land, Freek R ; van der Burg, Sjoerd H ; Homs, Marjolein Y V ; Lolkema, Martijn P ; Aerts, Joachim G J V ; van Eijck, Casper H J
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2022-06, Vol.12 (6), p.e060431
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High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments
Author / Creator:Deger, Teoman ; Boers, Ruben G. ; de Weerd, Vanja ; Angus, Lindsay ; van der Put, Marjolijn M. J. ; Boers, Joachim B. ; Azmani, Z. ; van IJcken, Wilfred F. J. ; Grünhagen, Dirk J. ; van Dessel, Lisanne F. ; Lolkema, Martijn P. J. K. ; Verhoef, Cornelis ; Sleijfer, Stefan ; Martens, John W. M. ; Gribnau, Joost ; Wilting, Saskia M.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2021-12, Vol.13 (1), p.196-196, Article 196
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Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients
Author / Creator:Valle-Inclan, Jose Espejo ; Stangl, Christina ; de Jong, Anouk C. ; van Dessel, Lisanne F. ; van Roosmalen, Markus J. ; Helmijr, Jean C. A. ; Renkens, Ivo ; Janssen, Roel ; de Blank, Sam ; de Witte, Chris J. ; Martens, John W. M. ; Jansen, Maurice P. H. M. ; Lolkema, Martijn P. ; Kloosterman, Wigard P.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2021-05, Vol.13 (1), p.86-86, Article 86
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Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features
Author / Creator:Mendelaar, Pauline A. J. ; Smid, Marcel ; van Riet, Job ; Angus, Lindsay ; Labots, Mariette ; Steeghs, Neeltje ; Hendriks, Mathijs P. ; Cirkel, Geert A. ; van Rooijen, Johan M. ; Ten Tije, Albert J. ; Lolkema, Martijn P. ; Cuppen, Edwin ; Sleijfer, Stefan ; Martens, John W. M. ; Wilting, Saskia M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.3269-3269, Article 3269
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Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review
Author / Creator:Walraven, Maudy ; Witteveen, Petronella O. ; Lolkema, Martijn P. J. ; van Hillegersberg, R. ; Voest, Emile E. ; Verheul, H. M. W.
Publisher:Dordrecht: Springer Netherlands
Journal title:Angiogenesis (London), 2011-05, Vol.14 (2), p.135-141
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Pan-cancer whole-genome analyses of metastatic solid tumours
Author / Creator:Priestley, Peter ; Baber, Jonathan ; Lolkema, Martijn P. ; Steeghs, Neeltje ; de Bruijn, Ewart ; Shale, Charles ; Duyvesteyn, Korneel ; Haidari, Susan ; van Hoeck, Arne ; Onstenk, Wendy ; Roepman, Paul ; Voda, Mircea ; Bloemendal, Haiko J. ; Tjan-Heijnen, Vivianne C. G. ; van Herpen, Carla M. L. ; Labots, Mariette ; Witteveen, Petronella O. ; Smit, Egbert F. ; Sleijfer, Stefan ; Voest, Emile E. ; Cuppen, Edwin
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-11, Vol.575 (7781), p.210-216
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Realizing better doctor-patient dialogue about choices in palliative care and early phase clinical trial participation: towards an online value clarification tool (OnVaCT)
Author / Creator:van Lent, Liza G. G. ; Stoel, Nicole K. ; van Weert, Julia C. M. ; van Gurp, Jelle ; de Jonge, Maja J. A. ; Lolkema, Martijn P. ; Gort, Eelke H. ; Pulleman, Saskia M. ; Oomen-de Hoop, Esther ; Hasselaar, Jeroen ; van der Rijt, Carin C. D.
Publisher:England: BioMed Central Ltd
Journal title:BMC palliative care, 2019-11, Vol.18 (1), p.106-106, Article 106
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Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer
Author / Creator:Kocakavuk, Emre ; Anderson, Kevin J. ; Varn, Frederick S. ; Johnson, Kevin C. ; Amin, Samirkumar B. ; Sulman, Erik. P. ; Lolkema, Martijn P. ; Barthel, Floris P. ; Verhaak, Roel G. W.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-07, Vol.53 (7), p.1088-1096
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Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520
Author / Creator:Verheijen, Remy B. ; van der Biessen, Diane A. J. ; Hotte, Sebastien J. ; Siu, Lillian L. ; Spreafico, Anna ; de Jonge, Maja J. A. ; Pronk, Linda C. ; De Vos, Filip Y. F. L. ; Schnell, David ; Hirte, Hal W. ; Steeghs, Neeltje ; Lolkema, Martijn P.
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2019-02, Vol.14 (1), p.67-74
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The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

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The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets

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CopywriteR: DNA copy number detection from off-target sequence data

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Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features

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Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning

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Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples

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Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer

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A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors

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Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications

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mFast‐SeqS ‐based aneuploidy score in circulating cell‐free DNA is a prognostic biomarker in prostate cancer

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High‐throughput isolation of circulating tumor DNA: a comparison of automated platforms

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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phas...

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High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

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Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients

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Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features

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Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review

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Pan-cancer whole-genome analyses of metastatic solid tumours

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Realizing better doctor-patient dialogue about choices in palliative care and early phase clinical trial participation: towards an online value clarification tool (OnVaCT)

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Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer

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Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520

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