CTCF mediates dosage- and sequencecontext- dependent transcriptional insulation by forming local chr...
CTCF mediates dosage- and sequencecontext- dependent transcriptional insulation by forming local chromatin domains
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Publisher
New York: Nature Publishing Group
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Language
English
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Publisher
New York: Nature Publishing Group
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Contents
Insulators play a critical role in spatiotemporal gene regulation in animals. The evolutionarily conserved CCCTC-binding factor (CTCF) is required for insulator function in mammals, but not all of its binding sites act as insulators. Here we explore the sequence requirements of CTCF-mediated transcriptional insulation using a sensitive insulator re...
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Full title
CTCF mediates dosage- and sequencecontext- dependent transcriptional insulation by forming local chromatin domains
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TN_cdi_proquest_journals_2550311566
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2550311566
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00863-6
