EGFR activation limits the response of liver cancer to lenvatinib
EGFR activation limits the response of liver cancer to lenvatinib
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Author / Creator
Jin, Haojie , Shi, Yaoping , Lv, Yuanyuan , Yuan, Shengxian , Ramirez, Christel F. A. , Lieftink, Cor , Wang, Liqin , Wang, Siying , Wang, Cun , Dias, Matheus Henrique , Jochems, Fleur , Yang, Yuan , Bosma, Astrid , Hijmans, E. Marielle , de Groot, Marnix H. P. , Vegna, Serena , Cui, Dan , Zhou, Yangyang , Ling, Jing , Wang, Hui , Guo, Yuchen , Zheng, Xingling , Isima, Nikita , Wu, Haiqiu , Sun, Chong , Beijersbergen, Roderick L. , Akkari, Leila , Zhou, Weiping , Zhai, Bo , Qin, Wenxin and Bernards, René
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hepatocellular carcinoma (HCC)—the most common form of liver cancer—is an aggressive malignancy with few effective treatment options
1
. Lenvatinib is a small-molecule inhibitor of multiple receptor tyrosine kinases that is used for the treatment of patients with advanced HCC, but this drug has only limited clinical benefit
2
. Here, us...
Alternative Titles
Full title
EGFR activation limits the response of liver cancer to lenvatinib
Authors, Artists and Contributors
Author / Creator
Shi, Yaoping
Lv, Yuanyuan
Yuan, Shengxian
Ramirez, Christel F. A.
Lieftink, Cor
Wang, Liqin
Wang, Siying
Wang, Cun
Dias, Matheus Henrique
Jochems, Fleur
Yang, Yuan
Bosma, Astrid
Hijmans, E. Marielle
de Groot, Marnix H. P.
Vegna, Serena
Cui, Dan
Zhou, Yangyang
Ling, Jing
Wang, Hui
Guo, Yuchen
Zheng, Xingling
Isima, Nikita
Wu, Haiqiu
Sun, Chong
Beijersbergen, Roderick L.
Akkari, Leila
Zhou, Weiping
Zhai, Bo
Qin, Wenxin
Bernards, René
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2556441351
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556441351
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03741-7