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EGFR activation limits the response of liver cancer to lenvatinib

EGFR activation limits the response of liver cancer to lenvatinib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556441351

EGFR activation limits the response of liver cancer to lenvatinib

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC)—the most common form of liver cancer—is an aggressive malignancy with few effective treatment options
1
. Lenvatinib is a small-molecule inhibitor of multiple receptor tyrosine kinases that is used for the treatment of patients with advanced HCC, but this drug has only limited clinical benefit
2
. Here, us...

Alternative Titles

Full title

EGFR activation limits the response of liver cancer to lenvatinib

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2556441351

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556441351

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-03741-7

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