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Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyeli...

Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyeli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556905817

Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study

About this item

Full title

Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study

Publisher

Vienna: Springer Vienna

Journal title

Amino acids, 2021-08, Vol.53 (8), p.1279-1286

Language

English

Formats

Publication information

Publisher

Vienna: Springer Vienna

More information

Scope and Contents

Contents

The aim of this study was to assess the effect of newly synthesized derivatives of 4-aminopyridine (4-AP) on cuprizone-induced model of brain demyelination in mice. 4-AP is already approved for the treatment of walking difficulties in patients with multiple sclerosis. The model of demyelination was carried out by the administration of cuprizone to...

Alternative Titles

Full title

Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2556905817

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2556905817

Other Identifiers

ISSN

0939-4451

E-ISSN

1438-2199

DOI

10.1007/s00726-021-03035-2

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