Somatic mutation rates scale with lifespan across mammals
Somatic mutation rates scale with lifespan across mammals
About this item
Full title
Author / Creator
Cagan, Alex , Baez-Ortega, Adrian , Brzozowska, Natalia , Abascal, Federico , Coorens, Tim H H , Sanders, Mathijs A , Lawson, Andrew R J , Harvey, Luke M R , Bhosle, Shriram G , Jones, David , Alcantara, Raul E , Butler, Timothy M , Hooks, Yvette , Roberts, Kirsty , Anderson, Elizabeth , Flach, Edmund , Spiro, Simon , Januszczak, Inez , Wrigglesworth, Ethan , Perkins, Matthew W , Deaville, Robert , Druce, Megan , Bogeska, Ruzhica , Milsom, Michael D , Neumann, Bjoern , Gorman, Frank , Constantino-Casas, Fernando , Peachey, Laura , Bochynska, Diana , St John Smith, Ewan , Gerstung, Moritz , Campbell, Peter J , Murchison, Elizabeth P , Stratton, Michael R and Martincorena, Inigo
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
The rates and patterns of somatic mutation in normal tissues are largely unknown outside of humans. Comparative analyses can shed light on the diversity of mutagenesis across species and on long-standing hypotheses regarding the evolution of somatic mutation rates and their role in cancer and ageing. Here, we used whole-genome sequencing of 208 int...
Alternative Titles
Full title
Somatic mutation rates scale with lifespan across mammals
Authors, Artists and Contributors
Author / Creator
Baez-Ortega, Adrian
Brzozowska, Natalia
Abascal, Federico
Coorens, Tim H H
Sanders, Mathijs A
Lawson, Andrew R J
Harvey, Luke M R
Bhosle, Shriram G
Jones, David
Alcantara, Raul E
Butler, Timothy M
Hooks, Yvette
Roberts, Kirsty
Anderson, Elizabeth
Flach, Edmund
Spiro, Simon
Januszczak, Inez
Wrigglesworth, Ethan
Perkins, Matthew W
Deaville, Robert
Druce, Megan
Bogeska, Ruzhica
Milsom, Michael D
Neumann, Bjoern
Gorman, Frank
Constantino-Casas, Fernando
Peachey, Laura
Bochynska, Diana
St John Smith, Ewan
Gerstung, Moritz
Campbell, Peter J
Murchison, Elizabeth P
Stratton, Michael R
Martincorena, Inigo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2562654101
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2562654101
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.08.19.456982
How to access this item
https://www.proquest.com/docview/2562654101?pq-origsite=primo&accountid=13902
